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NIH Research News

Updates every hour. Last Updated: 1-Jun-2025 19:09 ET (1-Jun-2025 23:09 GMT/UTC)

1-Apr-2025

Combination immunotherapy shrank a variety of metastatic gastrointestinal cancers

NIH/National Cancer Institute
Peer-Reviewed Publication

A new form of tumor infiltrating lymphocyte (TIL) therapy, a form of personalized cancer immunotherapy, dramatically improved the treatment’s effectiveness in patients with metastatic gastrointestinal cancers, according to results of a clinical trial led by researchers at the National Institutes of Health (NIH). The findings, published April 1, 2025 in Nature Medicine, offer hope that this therapy could be used to treat a variety of solid tumors, which has so far eluded researchers developing cell-based therapies.

Journal: Nature Medicine

31-Mar-2025

Social factors help explain worse cardiovascular health among adults in rural vs. urban communities

NIH/National Heart, Lung and Blood Institute
Peer-Reviewed Publication

A research team funded by the National Institutes of Health (NIH) uncovered higher rates of heart disease and worse heart health affecting adults living in rural communities compared to urban areas and the factors that likely drive these differences.

Journal: JAMA Cardiology

26-Mar-2025

Daily physical activity, even at light intensities, linked to lower cancer risk

NIH/National Cancer Institute
Peer-Reviewed Publication

In a prospective cohort study of more than 85,000 adults in the United Kingdom, researchers at the National Institutes of Health (NIH) and University of Oxford found that individuals who engaged in light- and moderate-to-vigorous-intensity daily physical activity had a lower risk of cancer than individuals who were more sedentary. The findings, published March 26, 2025, in British Journal of Sports Medicine, are among the first to evaluate the cancer risk reduction associated with light-intensity activities such as doing errands and performing household chores.

Journal: British Journal of Sports Medicine

21-Mar-2025

Study illuminates the structural features of memory formation at the cellular and subcellular levels

NIH/National Institute of Mental Health

In a study supported by the National Institutes of Health (NIH), researchers revealed the structural underpinnings of memory formation across a broad network of neurons in the mouse brain. This work sheds light on the fundamentally flexible nature of how memories are made, detailing learning-related changes at the cellular and subcellular levels with unprecedented resolution. Understanding this flexibility may help explain why memory and learning processes sometimes go awry.

Journal: Science
Funder: NIH/National Institute of Mental Health, BRAIN Initiative, NIH/National Institute of Neurological Disorders and Stroke

21-Mar-2025

NIH researchers develop eye drops that slow vision loss in animals

NIH/National Eye Institute
Peer-Reviewed Publication

Researchers at the National Institutes of Health (NIH) have developed eye drops that extend vision in animal models of a group of inherited diseases that lead to progressive vision loss in humans, known as retinitis pigmentosa.

Journal: Communications Medicine
Funder: NIH/National Eye Institute, Fondazione Telethon, Research to Prevent Blindness

	
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