Space-based experiment opens new avenues in Alzheimer’s research — First structural analysis of Tottori-type amyloid β fibrils conducted in microgravity —
Peer-Reviewed Publication
Updates every hour. Last Updated: 25-Jun-2025 00:10 ET (25-Jun-2025 04:10 GMT/UTC)
A Japanese research team has harnessed the unique microgravity environment aboard the International Space Station (ISS) to elucidate, for the first time, the detailed structure of amyloid β fibrils bearing the Tottori-type familial mutation (D7N), a rare variant linked to Alzheimer's disease. This space-based breakthrough not only enabled structural analysis that is difficult on Earth but also provides new insights into how disease-related mutations affect fibril formation—paving the way for new therapeutic strategies.
Dr. Congrui Grace Jin and her colleagues from the University of Nebraska-Lincoln have worked for years on bio-manufacturing engineered living materials and have developed a synthetic lichen system that can form building materials with no outside intervention. Their latest study, funded by the NASA Innovative Advanced Concepts program and recently published in the Journal of Manufacturing Science and Engineering, applies this research to the autonomous construction of structures on Mars, using the planet’s regolith, which includes dust, sand and rocks.
WASHINGTON, D.C. — Each summer, students from across the country begin internships with the U.S. Naval Research Laboratory (NRL), gaining hands-on experience in science and technology. These internships take place at various NRL locations, including sites along the Potomac River in Washington, D.C., the Stennis Space Center in Mississippi, and Monterey Bay in California. Each hoping for career growth that will take them to new horizons.
In the ever-evolving landscape of geospatial technology, innovations are steadily advancing our capabilities in Earth monitoring and urban planning. Precise positioning technologies and geoinformation science have become essential for various applications, from scientific research on global climate change and earthquake monitoring to supporting major initiatives in satellite navigation and smart city development. This article explores recent advancements in the field, including improvements in Terrestrial Reference Frame accuracy, real-time seismic monitoring through Global Navigation Satellite Systems (GNSSs), the development of advanced hyperspectral imaging systems, new techniques for ionospheric irregularity detection, and the creation of three-dimensional (3D) building space datasets for urban planning. These developments, while incremental, collectively enhance our ability to understand and manage our planet's resources and urban environments with greater precision and insight.
An MIT study finds non-clinical information in patient messages, like typos, extra whitespace, or colorful language, can reduce the accuracy of a large language model deployed to make treatment recommendations. The LLMs were consistently less accurate for female patients, even when all gender markers were removed from the text.